ABP-7 Peptide – Premium Research Peptide for Actin & Albumin Studies
ABP-7 (Actin-Binding Peptide-7) is a synthetic heptapeptide composed of seven amino acids bearing the sequence Acetyl-LKKTETQ . This peptide represents the N-acylated 17-23 fragment derived from the larger molecule Thymosin Beta 4 (TB-4) and is sometimes referred to as a TB-500 Fragment .
Key Factual Details
| ATTRIBUTE | DETAIL |
|---|---|
| Chemical Name | ABP-7 Peptide (Actin-Binding Peptide-7) |
| Sequence | Acetyl-LKKTETQ |
| Molecular Weight | ~842.98 g/mol (approximate) |
| Form | Lyophilized powder |
| Purity | >99% (HPLC tested) |
| Origin | Synthetic peptide via solid-phase peptide synthesis |
| Classification | Thymosin Beta 4 fragment / TB-500 Fragment |
Mechanism of Action & Research Applications
The LKKTETQ sequence of ABP-7 is considered the central actin-binding domain found in Thymosin Beta 4 . Researchers investigate ABP-7 for its potential to:
-
Modulate Actin Polymerization: ABP-7 inhibits the polymerization of globular actin (G-actin) into filamentous actin (F-actin) through actin sequestration .
-
Support Cell Migration Studies: By influencing cytoskeletal dynamics, ABP-7 may help researchers study cell motility and shape alteration .
-
Investigate Tissue Repair: As a fragment of TB-4, ABP-7 is studied for its role in wound healing and tissue regeneration models .
-
Albumin-Binding Research: Research indicates ABP-7 may possess albumin-binding properties relevant to molecular transport and stability studies .
-
Explore Cellular Signaling: Investigations suggest potential interactions with signaling pathways involved in stress responses and metabolic regulation .
Research Dosing & Handling
All dosages are for in-vitro research use only and not for human consumption.
-
Typical Research Application: Studies use ABP-7 to probe actin dynamics, cellular migration, and cytoskeletal reorganization .
-
Storage: Store lyophilized powder at -20°C. Avoid repeated freeze-thaw cycles after reconstitution.
