Adamax Peptide – Advanced Nootropic Research Peptide for Cognitive Studies
Adamax Peptide (N-Acetyl Semax Adamantyl) – Cognitive Enhancement Research Compound
Adamax is a synthetic peptide derivative and an advanced analogue of Semax, developed as a nootropic and neuroprotective research compound . Often described as Semax modified with both N-terminal acetylation and a C-terminal adamantyl group, these structural modifications significantly enhance its stability, lipophilicity, and ability to cross the blood-brain barrier . Adamax is considered the most potent among Semax derivatives and is a valuable research tool for investigating cognitive enhancement, neuroprotection, and neuroplasticity . This research-grade peptide is strictly for laboratory investigation and is not intended for human consumption.
Key Factual Details
| ATTRIBUTE | DETAIL |
|---|---|
| Chemical Name | Adamax (N-Acetyl Semax Adamantyl) |
| Synonyms | Ac-MEHFPGP-Adam-NH₂ |
| Sequence | Ac-Met-Glu-His-Phe-Pro-Gly-Pro-Ala-Gly-NH₂ (one-letter: Ac-MEHFPGPAG) |
| Molecular Formula | C₅₀H₆₉N₁₁O₁₁S |
| Molecular Weight | ~1,032.23–1,033.21 g/mol |
| CAS Number | N/A (synthetic analogue) |
| Purity | ≥98% (HPLC verified) |
| Classification | Nootropic peptide / Semax analogue |
Mechanism of Action & Research Applications
Enhanced BDNF Signaling: Adamax works by increasing Brain-Derived Neurotrophic Factor (BDNF) levels and improving the sensitivity of TrkB receptors, particularly in the hippocampus, a region vital for memory and learning . This interaction promotes improved cognitive functions, such as memory retention, focus, and overall mental clarity .
Structural Modifications for Enhanced Potency: The N-terminal acetyl group and C-terminal adamantyl modification improve stability and resistance to enzymatic degradation. The adamantane moiety, in particular, allows for easier blood-brain barrier penetration, resulting in greater potency than standard Semax .
Research Applications:
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Cognitive Enhancement Studies: Investigating memory, focus, and executive function
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Neuroprotection Research: Exploring neuron shielding and damage prevention mechanisms
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Neurogenesis Studies: Examining neuron regeneration and brain plasticity
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Neurodegenerative Disease Models: Research into cognitive decline and neurological conditions
Research Parameters
All dosages are for in-vitro and preclinical research use only and are not intended for human consumption.
Reconstitution Protocol :
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Add 3.0 mL bacteriostatic water to 10 mg vial → final concentration of ~3.33 mg/mL
Research Dosing Regimen :
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Starting Dose: 300 µg daily (Weeks 1-2)
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Mid-Range Dose: 500–750 µg daily (Weeks 3-6)
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Maintenance Range: 500–1,000 µg once daily
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Cycle Length: 8-12 weeks, followed by an equal off-cycle period
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Administration: Subcutaneous injection
Storage:
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Lyophilized powder: Store at -20°C
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Reconstituted solution: Refrigerate at 2-8°C, use within 1-2 weeks; avoid freeze-thaw cycles
Order Adamax Today – Request a quote for your cognitive or neuroprotection research project. Available in various pack sizes with Certificate of Analysis. Contact our sales team for bulk pricing and custom synthesis inquiries
